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In rodent studies, exendin-4 and dulaglutide have been detected in the brain following systemic administration, supporting their ability to engage central GLP-1 receptors, and these compounds are generally considered to be capable of penetrating the BBB (rskov et al., 1996
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Food producers therefore like to specify a best-before date that is as short as possible, even if the products would have a longer shelf life
Since then, he notes that both the FDA and European Medicines Agency (EMA) have investigated it and landed on the same conclusion: They dont think theres a cause and effect
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