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20 Since low BMD captures approximately 50% of the bone strength, and, at the current time, bone quality (the contributing factor for the other 50% of bone strength) cannot be measured clinically, 21,22 the T -score must be applied along with other validated risk factors for fracture risk that contribute to fracture risk independent of the BMD level
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When these proteins are abnormally expressed, the overload cytosolic free ferrous iron leads to intracellular ROS accumulation via the Fenton reaction, which eventually promotes lipid peroxides formation and ferroptosis occurrence (186)
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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