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Belli T, Ribeiro LF, Ackermann MA, Baldissera V, Gobatto CA, Galdino da Silva R
When considering the function of gut-derived GLP-1, it is difficult to ignore the metabolic effects of nutrient-derived energy in addition to the direct actions of GLP-1 itself
Recent research surprisingly demonstrated that serotonin-secreting enterochromaffin cells were the major chemical sensors for vagal afferent neurons in the proximal duodenum, whereas Glp1r -expressing ND neurons predominantly innervated muscle layers of the stomach and responded to stretch rather than to chemical stimuli entering the duodenum 46
Same monitoring rules, same dose-timing considerations, same red flags
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