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Glycine regulates protein turnover by activating protein kinase B/mammalian target of rapamycin and by inhibiting MuRF1 and atrogin-1 gene expression in C2C12 myoblasts
MOTS-c is administered subcutaneously, often on a 3 to 5 times per week schedule
A lower activity than predicted would mean a negative impact coming from the backbone modification
Furthermore, polymorphisms were also observed in other isoenzymes of the mu class: i.e
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