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In clinical trials, tirzepatide achieved a mean apnea-hypopnea index reduction of up to 63%, with meaningful improvements in sleep apnea symptoms both with and without positive airway pressure therapy

Nikolaidis LA, Elahi D, Hentosz T, Doverspike A, Huerbin R, Zourelias L, Stolarski C, Shen YT, Shannon RP: Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy