![AG924000: β-D-Lac-Ethyl-Azide Pack Size:1 g Fmoc-Ser[β-Gal(Ac)4-(1-3)-α-GalNAc(Ac)2]-OH](https://cdn.shopify.com/s/files/1/0810/4889/5786/files/AG924000-R.svg?v=1700851569)
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Fmoc-Ser[β-Gal(Ac)4-(1-3)-α-GalNAc(Ac)2]-OH
This compound enables the construction of hepatocyte-targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR)
The installed glycan is O-GlcNAc (GlcNAcβ-O-Ser/Thr)
Fmoc-Ser(β-D-Gal(1-3)[β-D-GlcNAc(1-6)]-α-D-GalNAc)-OH
AG924000: β-D-Lac-Ethyl-Azide Pack Size:1 g Fmoc-Ser[β-Gal(Ac)4-(1-3)-α-GalNAc(Ac)2]-OHC14H25N3O11 411. 36 A D lactose ligand equipped with an azide functionalized linker through a short ethyl spacer. The terminal azide can be covalently coupled to alkyne partners via copper catalyzed azide alkyne cycloaddition (CuAAC), or to dibenzocyclooctyne (DBCO) and related strained alkynes using copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound provides a lactose (Gal1 4Glc) building block for glycoconjugate
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