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25 / An α-mannose-6-phosphate (Man6P) ligand equipped with a terminal carboxylic acid through a short butyl spacer
GalNAcα1-O-Ser) equipped with a biotin tag through an amide bond
and mechanism of action studies
6-(2-Acetamido-2-deoxy-β-D-Galactopyranosyl-oxy) hexanoic acid (Peracetate)
GA421005: Fmoc-Ser(Gal(Ac)4-α-D)-OH Pack Size:25 mg 25 / An α-mannose-6-phosphate (Man6P)C32H35NO14 657. 62 An Fmoc protected L serine building block carrying an D galactose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as four acetate esters (Ac4), which keep the glycan inert
