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GLP-1s (being brand-name specialty injectables) typically sit in the highest tier, with coinsurance or high copays
Journal reference: Harnessing Facebook to Investigate Real-World Mentions of Adverse Events of Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 RA) Medications: Observational Study of Facebook Posts From 2022 to 2024
Most mild reactions (redness, soreness, mild bruising) come from the needle piercing the tissue or from the volume of fluid entering a small area
In July 2021, the FDA issued Ardelyx a Complete Response Letter in which it stated that the molecules effect size was small and of unclear clinical significance. Then, in November 2022, an FDA advisory committee voted 9-4 that Xphozahs benefits outweighed its risks
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