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While the former is generally recommended for patients with uncomplicated obesity, while the latter may be more suitable for individuals with multiple cardiometabolic comorbidities
doi: 10.1056/NEJMoa1612917 23 HondaJ.KimuraT.SakaiS.MaruyamaH.TajiriK.MurakoshiN.et al
This will allow for the stratification of results based on the presence of pathological changes and permit the evaluation of an interventions effect on the risk of developing symptoms
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