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82070464 to SX, 81941022 to JW, 81530025 to JW], Strategic Priority Research Program of Chinese Academy of Sciences [Grant No
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A recent study demonstrated that neuroinflammation could evoke depressive symptoms such as anhedonia and motor retardation (Song and Wang, 2011) and to lead to chronic immune dysregulation ( Figure 2 Previous studies found that pro-inflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin (IL)-6, IL-1, and C-reactive protein (CRP), are markedly increased in the blood and CSF of patients with depression (Smith et al., 2018)
Rabanel J-M, Piec P-A, Landri S et al (2020) Transport of PEGylated-PLA nanoparticles across a blood brain barrier model, entry into neuronal cells and in vivo brain bioavailability
