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A notable example is the CUR-PPR interaction: while PPR enhances CURs bioavailability by inhibiting CYP3A4 and P-gpcritical enzymes for CUR metabolismvia competitive binding to their active sites, this inhibition prolongs systemic CUR exposure
Another important side effect to consider on GLP-1 agonists is substantial muscle loss due to rapid weight loss, which doesnt distinguish between losing fat or muscle
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