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There is no built-in safety mechanism like a pre-filled pen provides
Rosenthal SB
The safety profile of dual agonists is similar to pure GLP-1 agonists, with the main difference being slightly higher rates of GI side effects
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Tirzepatide Is Sufficient (Stay Put) If: You're close to your target weight: If tirzepatide has gotten you 8090% of the way to your goal, switching drugs mid-course introduces titration disruption and new side effects for a marginal numerical gain
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