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Other pharmacologic treatments included other opioids, alpha2-adrenergic agonists, anxiolytics, an herbal supplement, and placebo
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A 2013 Cochrane Review involving 23 randomized controlled trials and 2,467 patients compared methadone to any other pharmacologic treatment for the management of opioid withdrawal
Effects seen after administration: Vitamin B12 Injection Shows Quick Effects.-Picture Courtesy: The Well Dog Place Vitamin b12 when given as oral supplement, it takes time to reach systemic circulation thats why it takes time to show effects after administration
