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Its interesting to observe that the expanding indications of GLP-1 RAs are not simply following an organ-based logic, but rather reflecting a growing awareness that diabetes is a systemic cardiometabolic disease
The current criteria for bariatric surgery in adolescents are as follows: class 2 obesity, defined as BMI 35 kg/m 2 or 120% of the 95th percentile for age and sex, plus clinically significant disease or class 3 obesity, defined as BMI 40 kg/m 2 or 140% of the 95th percentile for age and sex
It works best when: Combined with sunscreen and skincare Paired with a nutrient-rich diet Taken consistently over time Think of it less like an overnight fix and more like a strategic ally for long-term skin wellness
PARP-1 (poly-ADP-ribose polymerase 1) is a DNA repair enzyme that consumes NAD + to synthesize poly-ADP-ribose chains at damage sites
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