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Between 50% and 65% of patients quit within the first year, usually over cost, side effects or coverage barriers
Interestingly, recent evidences indicate that GLP1R agonists can significantly reduce adverse cardiovascular events, renal dysfunction, and the incidence of stroke in the patients with diabetes 9,10,11,12
Current evidence suggests that tirzepatide's therapeutic effects do not require direct blood-brain barrier penetration
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