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Poor gastrointestinal tolerance and malnutrition caused by appetite suppression, as well as micronutrient deficiencies, may exacerbate muscle loss
Patients should be advised about the urine discoloration (to avoid alarm) and counseled to report any persistent side effects
Recent developments include CMS unveiling its BALANCE model, a voluntary Medicare and Medicaid coverage pathway that includes price negotiations and supplemental lifestyle support, with coverage beginning in 2026 for Medicaid and 2027 for Medicare Part D [2]
That kind of improvement can be transformative
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