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Prepared formulations should be kept refrigerated and used within their stability window
The finding shifted understanding of how mitochondria communicate beyond energy production, signaling through circulating peptides that reach distant tissues
Among the 25 studies included in the qualitative synthesis (16 in the meta-analysis), 15 focused specifically on serum cobalamin changes (reported by baseline and post-treatment means and standard deviations in pg/mL) and 10 reported homocysteine outcomes (means and standard deviations in mmol/L)
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