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intramuscular use is limited to small, divided volumes
Participants began with a starting dose of 0.25 mg per week for both cagrilintide and semaglutide, with the doses co-escalated every four weeks (to 0.5 mg, 1.0 mg, and 1.7 mg) until reaching the maintenance dose of 2.4 mg per week for each medication after 16 weeks
Meguid MM, Fetissov SO, Blaha V, Yang ZJ (2000a)
The observed synergistic effect suggests that both macrophages and mast cells play a significant role in the early stages of atherosclerosis
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