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Key Takeaways GLP-1 medications can slow digestion, which may contribute to constipation, bloating, cramping, and other GI symptoms
Anyone with obesity, diabetes, digestive disease, a history of pancreatitis, gallbladder problems, kidney disease, or pregnancy plans should seek medical advice first
Ruth Loos, a genetic epidemiologist at the University of Copenhagen , who was not involved in the study, noted that the extra weight loss, on average, may not seem like a lot, but that for those with two copies of the GLP1R variant, it was more than 10% of the total weight loss that people experienced in the study population
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