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Osteoarthritis most commonly affects the hands, lower back, neck, and weight-bearing joints such as the knees, hips, and feet
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This differential efficiency of reprogramming was also reflected in the transcriptomes of these cells, as evaluated by the enrichment of a reprogramming score composed of genes previously reported in MEFs that are poised to reprogram at 72 h of OSKM expression 48 (Extended Data Fig
In rare cases, individuals may be allergic to certain components of the B12 shot
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