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Meal timing is a comfort and tolerability choice, not a dosing variable
Thus, direct GLP-1R signaling in SPNs might have clinical relevance as it may account for increased heart rate, a common side effect of GLP-1R agonist medications 21
Remember:GI side effects aren't responsible for most of the weight loss from semaglutide
Colonic ischemia in association with tirzepatide
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