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Ongoing and future trials might help identify individuals who can benefit from selenium supplementation, based, for instance, on individual selenium status or genetic profile
[16] [18] Alternative anxiolytic approaches that may be discussed with your GP include: Selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) as first-line pharmacological treatments for generalised anxiety disorder [15] [16] Cognitive behavioural therapy (CBT) or other evidence-based psychological interventions Gradual benzodiazepine tapering under medical supervision, potentially replacing alprazolam with longer-acting benzodiazepines before complete withdrawal Lifestyle modifications including regular exercise, sleep hygiene, and stress management techniques For weight management, if Wegovy proves intolerable, alternatives include other GLP-1 receptor agonists with different dosing schedules, orlistat (which works through a different mechanism), or comprehensive lifestyle intervention programmes
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They can be rapidly degraded by enzymes, leading to a short half-life
