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A further 1 to 3 hour delay may flatten the Cmax without substantially changing total AUC exposure, based on the drug's absorption-rate limited pharmacokinetics described in its FDA label [3]
Eng et al., J Biol Chem, 1992 Parkes et al., Diabetes Care, 2013 #GLP1 #DrugDiscovery #FromBenchToBedside #NephMadness #MedicalEducation #Endocrinology #Nephrology GLP-1 Receptor Agonists from Gila Monster Venom GLP-1: from lizard venom to modern medicine One of the most fascinating origin stories in pharmacology
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