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While specific risk factors for developing joint pain from semaglutide are not well-documented, general risk factors for joint pain, such as age, previous joint issues, and underlying inflammatory conditions, may play a role
Prior to the recommendations of the CANTOS study, conventional therapy regimens have neglected the role of inflammation in atherosclerosis (Weber and Noels, 2011)
2017;313(4):G34252
New York Medicaid data shows only 4,200 Wegovy prescriptions filled in 2025 despite approximately 240,000 eligible enrollees, suggesting the lifestyle intervention requirement functions as a practical barrier
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