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The dose was MIC-informed: our in vitro MIC was 15.625 g/mL, and the intragastric concentration (~ 15 g/mL) was selected to achieve approximately 1MIC in the gastric lumen, prioritizing local (topical) gastric exposure over systemic delivery while minimizing vehicle load
Investigation of the possible biological reasons for the wide range of peroxiredoxin hyperoxidation sensitivities will undoubtedly be an interesting area for future research
Allergic reactions: Allergic reactions including anaphylaxis have been reported with diclofenac and glucocorticoids
Gupta S, Melnyk S, Kruger W (2013) Cystathionine -synthase-deficient mice thrive on a low-methionine diet
