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However, Lip-1 administration abolished the antitumor effects of erastin (Zhang et al., 2019)
Early studies suggest GHK-Cu may modulate inflammatory cytokines (IL-6, TNF-) at higher doses, but clinical relevance at therapeutic doses in humans is not well-established
Starting with high doses may lead to mental overstimulation or irritability
Even then, the direct weight loss benefit is described as modest compared with hormone-targeted interventions, so the delivery problem is not the only limitation
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