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Because HSF1-mediated upregulation of HSP70/HSP90 requires transcription and translation, an increase in newly synthesized HSP70/HSP90 occurs with a delay
Lubna Elahi
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To integrate possible mechanistic events, a unified proposal for the role of cuproptosis in Wilson disease is suggested: (1) Published data support that copper ions induce oxidative stress by generating ROS, including hydroxyl radicals and H 2 O 2 , via the Haber-Weiss and Fenton reactions [21,27,45-49,59,77,90-92]
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