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GLP-1 analogues have not been shown to worsen depression or mental health conditions

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In type 2 diabetes, regain averaged 2.03 kg.[7][1] Key trials confirm this: STEP 1 extension saw two-thirds of lost weight return over a year off semaglutide

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Cardiovascular benefits of GLP-1-based therapies in patients with diabetes mellitus type 2: Effects on endothelial and vascular dysfunction beyond glycemic control

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Richard Siegel, a Tufts endocrinologist, to prescribe Wegovy in 2024 and then switch to Zepbound

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