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Importantly, this interaction was disrupted when WIPI2 was mutagenized in the domain for ATG16L binding, suggesting that MYTHO binding happens only when the WIPI2-ATG16L complex is formed
3 DAs should be used conservatively in older patients or patients with cognitive problems or dementia, due to the increased likelihood of developing intolerable adverse effects
[Abstract] Timeline and three different Thyroxine hormone (T4) treatment schemes
RT-PCR was done using a standard SYBR-green PCR kit (SYBR Premix EX TaqTM II, Takara), and the gene-specific PCR amplification was conducted using the Applied Biosystems StepOnePlus Real-Time PCR System (Applied Biosystems, USA)
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