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Based on UK data from the NBSR and BOMSS, patients can anticipate the following expected outcomes : Excess weight loss of approximately 5070% within the first 1218 months post-operatively, though results vary by centre and individual factors [11] Significant improvement or remission of obesity-related comorbidities, including type 2 diabetes (remission rates broadly in the range of 5060% at one to two years), hypertension, dyslipidaemia, and obstructive sleep apnoea [11] Improved quality of life, mobility, and psychological wellbeing Reduced long-term cardiovascular risk However, as with any surgical procedure, sleeve gastrectomy carries risks that must be clearly communicated during the consent process

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Patients were followed up for 180 days from the end of the wash-out period

2023 [40] conducted a post hoc analysis of the Harmony trial evaluating the effect of albiglutide versus placebo on reducing cardiovascular events in patients with T2DM and CVD with background use of SGLT-2is