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Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines
A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
In addition, the investigators reported that DA-CH5 was superior to Liraglutide in reducing the activation of microglia and astrocyte (helper cells that maintain the health of neurons), improving energy production in cells (mitochondrial activity), and boosting cellular waste disposal (autophagy)