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MesciPZadiSLobsigerCSMillecampsSEscartinCSeilheanDet al
In the context of weight management therapy, this may involve patient-specific considerations such as dosage instructions, treatment tolerance, medication history, or practical needs related to the prescription
The net effect is a significant reduction in spontaneous caloric intake and, with it, clinically significant weight loss
Abbreviations LC: L-carnitine TC: Total carnitine TMAO: Trimethylamine-N-oxide CHO: Carbohydrates IGF-1: Insulin-like growth factor-1 PI3K: Phosphoinositide-3-kinase Akt: Protein kinase B mTOR: Mammalian target of rapamycin S6K: S6 kinase 4E-BP: 4E-binding protein FoxO: Forkhead box O MuRF-1: Muscle-specific RING finger-1 atrogin-1: Muscle atrophy F-box mRNA: Messenger RNA BMI: Body mass index ROS: Reactive oxygen species References Bremer J
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