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In this study, we report that the insulinotropic effect of the triagonist IUB447 is mainly due to its direct binding to the GLP-1R, leading to an increase in both Gq signalling and TRPM5 activity
The article explains that while a deductible is unmet, a branded GLP-1 fill costs its full price rather than a copay, and only once the deductible is satisfied does the copay structure apply
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