Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms

), Organic Turmeric (rhizome) ( Curcuma longa ), Reishi (fruiting body) ( Ganoderma lucidum ), Organic Hyssop (leaf, stem) ( Hyssopus officinalis ), Organic Burdock (root) ( Arctium lappa ), Organic Fennel (seed) ( Foeniculum vulgare ), Organic Lemon Peel ( Citrus limon ) L-glutathione (reduced) 125 mg Take 1 capsule, 3 times daily
However, there are specific groups for which copper peptide serums may be best suited
Whilst weight loss is modest (typically 35% beyond lifestyle intervention), orlistat has an extensive safety record spanning over two decades