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As a co-therapy like in case of combined collagen crosslinking (CXL) and intrastromal corneal ring segment (ICRS) implantation to treat keratoconic eyes, no adverse effect from the riboflavin injections were reported (32)
Journal Reference : Fares Qeadan
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The barrier will still be an investigational new drug application in an FDA designated disease indication (of which for many of these peptide use cases, there isn't one)
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