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Key findings across this body of work include: Improved performance on the Reading the Mind in the Eyes test a validated measure of social cognition in multiple randomized placebo-controlled trials Enhanced encoding of positive social memories following administration in healthy men Increased gaze directed toward the eye region of human faces, a mechanism proposed to underlie improved emotion recognition Context-dependent effects: some studies report that oxytocin heightens sensitivity to both positive and negative social cues, not exclusively pro-social outcomes Importantly, results are not consistently replicated across studies, with several large pre-registered trials failing to observe significant social cognition benefits

They furthermore identified NRF2 as key regulator of immune-modulating genes, linking oxidative stress with the induction of cyclooxygenase 2 (COX2) in an ATF4-dependent manner

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Both options include provider supervision, 503A compounded medication sourced from a licensed pharmacy, dosing instructions, and follow-up