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For menopausal women, these effects are usually manageable and preferable to continued metabolic decline
Arch Biochem Biophys 95:483493 Loewus MW, Bedgar DL, Saito K, Loewus FA (1990) Conversion of Lsorbosone to l-ascorbic acid by a NADP dependent dehydrogenase in bean and spinach leaf
"It is a progressive condition eventually leading to kidney failure requiring dialysis or kidney transplantation and is associated with premature death, mostly from heart disease
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