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372,373 The mTOR pathway plays a significant role in DPN development by affecting autophagy and apoptosis in Schwann cells, myelin formation, and lipid metabolism, thereby influencing myelin and axonal integrity
However, some patients may experience them due to factors such as rapid weight loss, dehydration, or electrolyte imbalances during treatment
FDA Label Blume-Peytavi U, et al
An increase in global peripapillary choroid thickness [13, 15, 16], optic nerve head minimum rim width [13, 17] and retinal nerve fibre layer thickness [14] are reported in both males and females
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