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At 32 weeks, the reduction in HbA1c levels with CagriSema was statistically superior to cagrilintide alone, but not statistically greater than semaglutide 6
GLP-1 analogs and DPP-4 inhibitors in type 2 diabetes therapy: Review of head-to-head clinical trials
When discussing gastrointestinal side effects, including heartburn, with your prescriber, it is helpful to: Keep a symptom diary noting when symptoms occur, their severity, duration, and any potential triggers Report all concurrent medications and supplements , as some including non-steroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics can independently worsen reflux or interact with gastrointestinal function [8] [9] Ask about dose titration options if symptoms are significantly affecting your quality of life Discuss whether a formal GORD assessment is warranted , particularly if symptoms are persistent your GP may consider Helicobacter pylori testing or referral for endoscopy based on NICE CKS and NG12 criteria Your prescriber may refer you to a gastroenterologist if symptoms are complex or do not resolve with standard management
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