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PE-22-28 (Mini-Spadin) blocks TREK-1 potassium channels with ~100-fold greater potency than its parent compound, demonstrating BDNF upregulation, rapid neurogenesis within 4 days, and cognitive benefits in stroke models (Djillani et al., 2017 in Frontiers in Pharmacology)
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2008;1780(11):1304-1317.[DOI] 21
Methycobals production is supported by WHO-GMP certification, which guarantees the products effectiveness
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