I understand how these might slow the rate of progression in a general sense using multiple mechanisms. For example, diabetes, cardiovascular disease, and obesity are all risk factors for developing dementia, so using GLP-1 agonists to improve these various aspects of health may, in turn, protect cognition
The Fella Health program not only supports weight loss with a biology-first approach, but also through behavior change
It enhances the activity of CREB, a transcription factor that regulates the expression of genes involved in memory consolidation, and promotes the production of BDNF, or brain-derived neurotrophic factor, a protein that acts as a kind of molecular fertilizer for neurons, supporting their survival, growth, and the formation of new synaptic connections [15]
Hanna, M., Jaqua, E., Nguyen, V., & Clay, J