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Semaglutide reduces insulin requirements almost independent of weight loss in the early course of the treatment. In ADJUST-T1D, participants receiving semaglutide started the drug at a once-weekly 0.25 mg dose for 4 weeks, increasing to 0.5 mg at 4 weeks and 1 mg at 8 weeks for the remainder of the trial
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These findings confirmed that GLP-1RA had a certain influence on the occurrence and development of tumors
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