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Unlike natural IGF-1, IGF-1 LR3 has been structurally modified to reduce binding to IGF-binding proteins, which allows it to remain active longer in experimental models
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"This new study provides real-world evidence for its impact on Alzheimer's disease, even though preclinical research has suggested that semaglutide may protect against neurodegeneration and neuroinflammation," Xu said in a Case Western news release
It just so happened, however, that Ozempic was incredibly effective for weight loss, to the point where it got its own version FDA-approved just for that, Wegovy , and spurred a whole new generation of weight-management medications
