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Pernicious anemia requires lifelong treatment, and studies have shown substantial rates of noncompliance with vitamin B12 supplementation (45)

Limitations of animal research: Rat healing faster than human, young research animals heal better than aged humans, controlled injury models don't replicate complex human injuries perfectly, dosing conversions uncertain (body weight scaling imperfect), immune system differences affect inflammation and healing

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However, effects of BPC 157 on vascular tone and intracellular Src-Cav-1-eNOS signaling are still not understood