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Starting at a lower dose and gradually increasing helps reduce discomfort
Use the medication in defined periods, maintain with lifestyle between cycles
So, how does it compare to Wegovy
J Cardiovasc Transl Res 17(1):121132 Mahmod M, Pal N, Rayner J, Holloway C, Raman B, Dass S, Levelt E, Ariga R, Ferreira V, Banerjee R et al (2018) The interplay between metabolic alterations, diastolic strain rate and exercise capacity in mild heart failure with preserved ejection fraction: a cardiovascular magnetic resonance study
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