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A complete PA submission typically includes: Patient demographics, current BMI with date of measurement, weight history showing chronicity, qualifying comorbidities with ICD-10 codes, documented prior weight-loss attempts and outcomes, prior pharmacotherapy trials and reasons for failure or intolerance, the prescriber's clinical rationale for the requested medication, and contraindications to alternative therapies if relevant
Preclinical studies have shown that GLP-1 receptor activation decreases motivation to work for palatable food rewards and reduces consumption of highly rewarding foods
They accuse Novo Nordisk and Eli Lilly & Co
However, most patients dont come in describing dramatic differences, just subtle shifts
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