retatrutide type 2 diabetes phase 2 trial results III study demonstrates 30% weight loss Retatrutide study sees significant weight

While no supplement can replace prescription GLP-1 therapy, the right ingredients can help support appetite control, digestive comfort, metabolic health, and essential nutrient intake.* Below is a guide to the best OTC GLP-1friendly supplements, plus key ingredients to look for

Proteins: Two pounds of chicken breast

Fenugreek (Trigonella foenum-graecum) contains bioactive compounds, including 4-hydroxyisoleucine, that have demonstrated the ability to increase glucose-dependent insulin secretion in human beta-islet cells

The injection still wins when the goal is the largest possible weight loss, when type 2 diabetes and cardiovascular risk are part of the picture, or when a patient is already doing well on tirzepatide