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Preclinical models, particularly those using MPTP-induced PD models in rodents, have demonstrated that GLP-1 RAs can reduce the accumulation of -synuclein
doi: 10.1016/j.jdiacomp.2014.12.006 27 LamersDFamullaSWronkowitzNHartwigSLehrSOuwensDMet al
They are the basis for the precise regulation of carnitine transport between different tissues and different subcellular compartments within the cell, maintaining the balance of the carnitine pool
Figure 3: How to Win in Diabetes and Obesity: Address Remaining Unmet Needs Its unlikely that any single therapy will be able to satisfy all unmet needs
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