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Additionally, GLP-1 antagonist receptors decrease the circulating concentrations of angiotensin II, an effect that also plays a role in the observed increase in renal sodium wasting
Published Phase 2 trial data (NEJM, 2023) demonstrated substantial reductions in body weight in some participants exceeding 20% over approximately 48 weeks making retatrutide one of the most potent agents currently in development for obesity and metabolic disease
Five things to know about using GLP-1 drugs for weight loss The new Wegovy pill the first GLP1 weightloss medication you can take by mouth is creating even more interest in a drug category that was already booming
This distinction is not merely academic
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