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This cascade of events drives both inflammation and tissue degradation, perpetuating a cycle of joint destruction that worsens the progression of OA
If peptide-based approaches can provide meaningful benefit at lower cost and with fewer side effects, that combination would make them attractive as either standalone or adjunctive therapy
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However, following baseline we only assessed dietary intake for 4 consecutive days prior to each of the two testing sessions at weeks 4 and 8 (8 out of 56 days) which constitutes a small portion of the dietary intake, approximately 86%, not accounted for during the study
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